Vitamin D receptor(s): In the nucleus but also at membranes?

Blockade of Opioid Receptors Located in the Rat Nucleus Cuneiformis Reduced the Antinociceptive Responses of Local But not Systemic Administration of Morphine in Formalin Test

ABSTRACTPrevious studies have shown the role of opioid receptors located in the nucleus cuneiformis (CnF) in acute pain, but not in chronic pain models. In the present study, we have determined that possible effects of these receptors at the CnF on both early and late phases of formalin test following local and systemic morphine administration. Each rat was given a subcutaneous 50-μl injection ...

Vitamin D3 Induces Gene Expression of Ox-LDL Scavenger Receptors in Streptozotocin-Induced Diabetic Rat Aortas: New Insight into the Role of Vitamin D in Diabetic Atherosclerosis

Background: Several lines of evidence suggest that oxidized LDL (Ox-LDL) scavenger receptors play a crucial role in the genesis and progression of diabetic atherosclerosis. This study aimed to elucidate the effect of vitamin D3 on gene expression of lectin-like oxidized LDL receptor-1 (LOX-1), scavenger receptor-A (SR-A), Cluster of Differentiation 36 (CD36), and Cluster of Differentiation 68 (...

Review: vitamin D plus calcium, but not vitamin D alone, prevents osteoporotic fractures in older persons.

M e t h o d s Data sources: 10 databases, lists of conference abstracts, bibliographies of relevant studies, and contact with researchers in the field. Study selection and assessment: Randomized and quasi-randomized controlled trials (RCTs) that compared vitamin D or a vitamin D analogue (alone or in combination with calcium) with placebo, no intervention, or calcium alone in postmenopausal wom...

The role of locus coeruleus nucleus TRPV1 receptors in the development and expression of morphine dependence

Objective(s): This study investigated the role of locus coeruleus (LC) nucleus TRPV1 receptors (TRPV1r) in the expression and development of morphine physical dependence by intra-LC administration of AMG9810 (selective TRPV1r antagonist) in male Wistar rats. Materials and Methods: For assessing the development of morphine dependence, AMG9810 (0.0...

The effect of vitamin D supplementation on the size of uterine leiomyoma in women with vitamin D deficiency